LowTE Florida Methyl Factors+
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You don’t notice it at the conscious level, but, at the cellular level, 24 hours a day and seven days a week, your body is hard at work facilitating an enzymatic process called methylation.
Methylation is essential for optimal cardiovascular, reproductive, hormonal, and neurological function, as well as aiding the natural detoxification process.
For reasons we’ll discuss here, in a huge percentage of people, the process of methylation does not properly occur and therefore these individuals miss out on the maximum benefits of methylation, with potentially serious health consequences.
Fortunately, supplementation in the form of LowTE Florida Methyl Factors+ can counteract poor methylation and restore optimal methylation, thereby potentially dramatically improving physical and mental health.
What is methylation and why is it critical for anti-aging health?
Methylation occurs when a group of three hydrogen and one carbon atom (-CH3), which form a methyl group, are added to molecules in the body, thereby catalyzing various functions critical for health.
The metabolite SAMe (S-adenosylmethionine), a universal methyl donor found in every cell of the human body, donates CH3 readily, conferring functional benefits to numerous systems — the neurological, endocrine (hormones), and cardiovascular, just to name a few.
Methylation also facilitates greater fat metabolism, neurotransmitter production, DNA production, among other benefits.
A bioactive form of the B-vitamin folate called methyl folate, or “active folate,” abbreviated as 5-MTHF, is responsible for activating SAMe. With adequate 5-MTHF levels, methylation hums along as it’s meant to.
In healthy individuals, in the absence of any genetic issues or environmental factors that compromise methylation, sufficient levels of 5-MTHF can be easily synthesized from raw materials sourced through the diet in the form of:
- Green leafy vegetables, especially cruciferous veggies (broccoli, cauliflower, spinach, etc.)
- Avocado
- Legumes (beans)
- Asparagus
However, this is where the snag comes in that limit’s methylation in many people:
The enzyme that controls the production of 5-MTHF, methylenetetrahydrofolate reductase (MTHFR), does not work properly in a vast swathe of patients that I see at my LowTE Florida practice.
Research backs up my clinical experience: “Up to 40% of the population may have an MTHFR mutation of some kind,” per Psychology Today.
By some other estimates, the percentage of Americans with MTHFR mutations may be as high as 60%.
The consequences of an untreated MTHFR mutation are potentially severe: “The mental health issues linked to having an MTHFR mutation [are] depression, bipolar disorder, schizophrenia, attention-deficit hyperactivity disorder (ADHD), or autism,” Psychology Today notes. “MTHFR mutations also increase the risk of several physical health problems, including but not limited to cardiovascular disease and stroke, recurrent early miscarriage, migraine with aura, osteoporosis, and some cancers.”
While genetic mutations are the most common culprit of poor methylation, numerous other factors can also play a role: “Many lifestyle factors, including diet, obesity, physical activity, tobacco smoking, alcohol consumption, environmental pollutants and psychological stress, have been shown to modify DNA methylation patterns,” according to Lupus Science & Medicine
Poor methylation devastates the body’s ability to produce critical hormones, neurotransmitters, and compounds
As we alluded to previously, impaired methylation limits the body’s ability to synthesize crucial compounds, the names of which you are likely familiar with.
The compounds supported by proper methylation include but are not limited to:
- Serotonin
- Nitric oxide (NO)
- Melatonin, a critical neurotransmitter for optimal sleep and multiple other functions
- Coenzyme Q10 (CoQ10)
- Glutathione, known as the “master antioxidant” critical for protecting cells from the damage caused by oxidative stress
- Cysteine
- Adenosine triphosphate (ATP), the main energy source for human cells
Without going into detail on the vital role that each of these hormones, neurotransmitters, and signaling proteins play in maintaining optimal health, particularly in older patients, maintaining optimal levels of each of the above is absolutely essential to slow down the aging process and maintain peak mental and physical health.
Indeed, impaired methylation over a long enough timeline has been demonstrated to contribute to numerous chronic diseases, including potentially, cancer.
From the Journal of Medical Genetics (emphasis extra):
“DNA methylation is not just for basic scientists anymore. There is a growing awareness in the medical field that having the correct pattern of genomic methylation is essential for healthy cells and organs. If methylation patterns are not properly established or maintained, disorders as diverse as mental retardation, immune deficiency, and sporadic or inherited cancers may follow. Through inappropriate silencing of growth regulating genes and simultaneous destabilization of whole chromosomes, methylation defects help create a chaotic state from which cancer cells evolve. Methylation defects are present in cells before the onset of obvious malignancy and therefore cannot be explained simply as a consequence of a deregulated cancer cell.”
For all patients, I universally recommend regular supplementation with LowTE Florida Methyl Factors+.
Methyl Factors+ delivers essential nutrients for patients with methylation challenges
If, indeed, you are one of the 40-60% of patients with an MHTFR mutation that hinders your body’s natural methylation capacity, or even if you don’t have any genetic issues but just want to supplement your methylation, LowTE Florida Methyl Factors+ includes the industry-leading cocktail of nutrients prove to effectively increase methylation.
Each easy-to-swallow LowTE Florida Methyl Factors+ includes:
- L-5-methyl-tetrahydrofolate (5-MTHF), the methylated form of folate that bypasses any need for the conversion of dietary folate in individuals with compromised methylenetetrahydrofolate reductase (MTHFR) function. “Dietary supplements that avoid synthetic folic acid and support the one-carbon and the folate cycles in both men and women have positive benefits and improve fertility, especially for carriers of the MTHFR SNPs,” notes the International Journal of Molecular Sciences.
- Trimethylglycine (TMG), a form of the vital amino acid glycine that acts as a methyl donor and helps to stimulate S-adenosylmethionine (SAM) production, the central role of which in the process of methylation is described above
- Methylcobalamin, the methylated form of vitamin B-12
- Riboflavin (vitamin B2)
- Pyridoxine (vitamin B6)
Additionally, each Methyl Factors+ ingredient is:
- Non-GMO
- Hypoallergenic
- Natural (not artificial)
Unlike other supplement manufacturers that source their products from abroad and often include sub-par ingredients from Third World suppliers, we are proud to produce Methyl Factors+ right here in the United States.
Get in touch with LowTE Florida to learn more about our anti-aging products and services
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